Since 1977, this outstanding book has been the immunology reference of choice for both veterinary students and practitioners. It’s the only complete resource on the subject, featuring a straightforward presentation of basic immunologic principles with comprehensive information on the most significant immunological diseases and responses seen in domestic animals. This meticulously updated new edition explores the latest advances in the field and provides a wealth of clinical examples that illustrate and clarify important concepts.

• Clearly explains the general principles of immunology and applied immunology.
• Includes information on the most significant immunological diseases and immunological responses seen in domestic animals.
• Presents coverage of domestic mammal species in phylogenetic order: horse-cattle-sheep-pig-dog-cat-mouse-human.
• Provides clinical examples that demonstrate key immunologic principles.
• Offers expanded and updated references for all key sources in the literature.

• Features a new appendix that provides at-a-glance access to a comprehensive list of cytokines.
• Offers expanded coverage of complement and its critical importance to innate immunity.
• Discusses the latest information on the receptors of NK cells.
• Provides additional content on antibacterial peptides and their importance in inflammation and innate immunity.
• Includes coverage of newly identified cytokines, CD molecules, and IgA receptors.
• Examines new data on the functions of T cells, the effects of nematodes on eosinophils, and the latest DNA vaccines against West Nile virus and canine melanoma.
• Offers complete information on emerging diseases such as Stevens-Johnson syndrome, hemophagocytic syndrome, and autoimmune sarcolemmal disease in dogs, as well as common variable immunodeficiencies and immune mediated polysynovitis in horses.